Hirata S, Miya H, Mizuno K
Department of Orthopaedic Surgery, Kobe University School of Medicine, Japan.
Clin Orthop Relat Res. 1995 Jun(315):242-5.
The etiology of congenital pseudarthrosis of the clavicle remains obscure. The authors treated a 5-year-old boy with this rare disease. Clinical history and radiographs confirmed the diagnosis. Surgical treatment of resection of the pseudarthrosis, autologous bone graft, and internal fixation with a small AO plate led to successful bone union. Histologic analysis of the pseudarthrosis showed that there were cartilaginous caps on the proximal and distal bony ends. The appearance of the cartilaginous caps were equivalent to that of developing physes. They were adding new bone to the bony ends, which also was confirmed by preoperative tetracycline labeling. These observations support the hypothesis that the pseudarthrosis is caused by failure of 2 ossification centers to fuse, as was previously proposed by others.
锁骨先天性假关节的病因仍不清楚。作者治疗了一名患有这种罕见疾病的5岁男孩。临床病史和X光片证实了诊断。对假关节进行切除、自体骨移植并用小型AO钢板进行内固定的手术治疗使骨成功愈合。对假关节的组织学分析表明，近端和远端骨端有软骨帽。软骨帽的外观与发育中的骺板相似。它们在向骨端添加新骨，术前四环素标记也证实了这一点。这些观察结果支持了假关节是由两个骨化中心未能融合引起的这一假说，这一假说此前已被其他人提出。
