Krokowski E
Strahlentherapie. 1978 Mar;154(3):147-60.
Is seems indispensable, in consideration of the present investigation results, to revise our actual therapeutic conception for cancer therapy! While palliative cancer therapy was greatly successful, it was not possible to obtain any decisive improvement of cancer recovery rates (in relation to similar stages or tumor volumes), in spite of all the therapeutic endeavour through the last twenty or twenty-five years. From almost 3000 analyses of metastatic growth and from numerous other experimental or clinical observations results as an explication that surgical treatment itself, on certain conditions, may release a relatively great number of metastases. Thus, the failure of our therapeutical endeavor is programmed, too, by the treatment! Consequences for diagnostics, precautions and therapy are discussed.
鉴于目前的研究结果,似乎有必要修正我们当前癌症治疗的实际理念!尽管姑息性癌症治疗取得了巨大成功,但尽管在过去二十或二十五年里付出了所有治疗努力,仍无法在癌症治愈率方面取得任何决定性的提高(相对于相似阶段或肿瘤体积)。从近3000例转移性生长分析以及众多其他实验或临床观察结果来看,有一个解释是,在某些情况下,手术治疗本身可能会释放出相对大量的转移灶。因此,我们治疗努力的失败也是由治疗本身所注定的!文中讨论了对诊断、预防措施和治疗的影响。