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环境样本库设计中的考量因素:国家生物监测样本库项目的经验

Considerations in the design of an environmental specimen bank: experiences of the National Biomonitoring Specimen Bank Program.

作者信息

Wise S A, Koster B J

机构信息

Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, USA.

出版信息

Environ Health Perspect. 1995 Apr;103 Suppl 3(Suppl 3):61-7. doi: 10.1289/ehp.95103s361.

Abstract

Since 1979 the National Institute of Standards and Technology (NIST) has been involved in environmental specimen banking activities as part of the National Biomonitoring Specimen Bank (NBSB). These activities have focused on the development of procedures for the collection, processing, analysis, and long-term storage of a variety of environmental specimens including: human liver, mussels and oysters, fish tissue (liver and muscle), marine mammal tissues (blubber, liver, and kidney), and marine sediments. The experiences of the NBSB can provide valuable information to assist in the design of new specimen bank efforts. Based on the experiences of the NBSB, the issues that should be addressed in the design and operation of a valid specimen bank program are presented.

摘要

自1979年以来,美国国家标准与技术研究院(NIST)一直参与环境样本库活动,作为国家生物监测样本库(NBSB)的一部分。这些活动主要集中在制定各种环境样本的采集、处理、分析和长期存储程序,包括:人类肝脏、贻贝和牡蛎、鱼类组织(肝脏和肌肉)、海洋哺乳动物组织(鲸脂、肝脏和肾脏)以及海洋沉积物。NBSB的经验可为协助设计新的样本库工作提供有价值的信息。基于NBSB的经验,本文提出了有效样本库计划在设计和运营中应解决的问题。

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