大肠杆菌铁氧化还原蛋白（黄素氧还蛋白）NADP +氧化还原酶基因的中断不影响厌氧生长，但增加了对百草枯的敏感性。
Interruption of the ferredoxin (flavodoxin) NADP+ oxidoreductase gene of Escherichia coli does not affect anaerobic growth but increases sensitivity to paraquat.
作者信息
Bianchi V, Haggård-Ljungquist E, Pontis E, Reichard P
机构信息
Department of Genetics, Stockholm University, Sweden.
出版信息
J Bacteriol. 1995 Aug;177(15):4528-31. doi: 10.1128/jb.177.15.4528-4531.1995.
Abstract
Ferredoxin (flavodoxin) NADP+ oxidoreductase participates in methionine biosynthesis and in the function of two anaerobic enzymes, pyruvate formate-lyase and ribonucleotide reductase. We prepared insertion mutants of Escherichia coli lacking a functional enzyme. They do not require methionine and they grow well anaerobically, but they show increased sensitivity to paraquat.
摘要
铁氧化还原蛋白（黄素氧还蛋白）NADP⁺氧化还原酶参与甲硫氨酸的生物合成以及两种厌氧酶（丙酮酸甲酸裂解酶和核糖核苷酸还原酶）的功能。我们制备了缺乏功能性该酶的大肠杆菌插入突变体。它们不需要甲硫氨酸，并且在厌氧条件下生长良好，但对百草枯表现出更高的敏感性。
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Interruption of the ferredoxin (flavodoxin) NADP+ oxidoreductase gene of Escherichia coli does not affect anaerobic growth but increases sensitivity to paraquat.大肠杆菌铁氧化还原蛋白（黄素氧还蛋白）NADP +氧化还原酶基因的中断不影响厌氧生长，但增加了对百草枯的敏感性。
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