Sofikitis N, Miyagawa I, Dimitriadis D, Zavos P, Sikka S, Hellstrom W
Department of Urology, Tottori University School of Medicine, Yonago, Japan.
J Urol. 1995 Sep;154(3):1030-4.
The effects of smoking on testicular function and sperm physiology were studied.
Left testicular biopsy was performed in 49 smokers and 28 nonsmokers. Seminal specimens from these men were analyzed.
Testosterone levels in the left testicular vein, left testicular androgen-binding protein secretion rate (in vitro), sperm motility, percentage of morphologically normal spermatozoa, sperm morphometric parameters and outcome of sperm function tests were significantly lower (p < 0.05) in smokers than in nonsmokers.
Morphological sperm abnormalities due to secretory dysfunction of the Leydig and Sertoli cells may be the cause of impaired sperm fertilizing capacity in smokers.
