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定量99mTc-MDP骨扫描能否用于预测微血管移植后骨骺板同种异体移植物的纵向生长?一项实验研究。

Can quantitative 99mTc-MDP bone scans be used to predict longitudinal growth of epiphyseal plate allografts after microvascular transplantation? An experimental study.

作者信息

Boyer M I, Gilday D, Kiral A, Nolan L, Bowen C V

机构信息

Division of Surgical Research, Hospital for Sick Children, Toronto, Ontario, Canada.

出版信息

Microsurgery. 1995;16(3):155-60. doi: 10.1002/micr.1920160308.

DOI:10.1002/micr.1920160308
PMID:7637624
Abstract

Allograft and autograft microvascular proximal tibial epiphyseal plate transplants were performed in female New Zealand White (NZW) rabbits to quantify the growth rate and total growth potential of immunosuppressed and nonimmunosuppressed rabbits. The purpose of this experiment is to examine whether the 99mTc-MDP radionuclide uptake of the transplanted epiphyseal plate at 1 week postoperatively, done to assess anastomotic patency of the transplant, could also serve as a predictor of eventual longitudinal growth of the transplant or replant. All transplants and replants demonstrating positive 99mTc-MDP uptake in the proximal tibial epiphyseal plate at 1 week showed continued longitudinal growth. The precise amount of 99mTc-MDP uptake, however, did not correlate with the amount of growth at 3 and 5 weeks follow-up.

摘要

对雌性新西兰白兔进行同种异体和自体微血管胫骨近端骨骺板移植,以量化免疫抑制和非免疫抑制兔子的生长速率和总生长潜力。本实验的目的是检验术后1周对移植骨骺板进行99mTc-MDP放射性核素摄取(用于评估移植吻合口通畅情况)是否也可作为移植或再植最终纵向生长的预测指标。所有在术后1周胫骨近端骨骺板显示99mTc-MDP摄取阳性的移植和再植均呈现持续纵向生长。然而,99mTc-MDP摄取的精确量与3周和5周随访时的生长量不相关。

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