Martínez Sánchez J, Salas Nieto J, Ruipérez Abizanda J A, Picó Aracil F, de la Morena Valenzuela G, Campos Peris J V, Ruiz Ros J A
Unidad de Cardiología, Hospital Universitario Virgen de la Arrixaca, Murcia.
Rev Esp Cardiol. 1995 Jul;48(7):467-72.
The aim of the present study was to determine the reliability of early exercise test to detect multivessel disease in survivors of an uncomplicated first anterior Q-wave myocardial infarction.
Among 100 consecutive patients 64 (aged 55 +/- 10 years) were included in the study. Thirty-four patients (53.1%) received thrombolytic therapy and this was considered successful, by means of non-invasive criteria, in 24 patients (37.5%). A standard symptom-limited exercise test, 11-15 days after myocardial infarction, and coronary arteriography, < 72 hours later, were performed in all patients.
On exercise test 6 (9.3%) patients developed significant ST segment depression, 48 (75%) significant ST segment elevation, 5 (7.8%) ST depression in inferior leads together with ST elevation in anterior leads and 3 (4.6%) angina. Of the 18 patients with multivessel disease 5 (27.8%) developed ST depression, 10 (55.5%) ST elevation, 1 (5.5%) ST depression in inferior leads together with ST elevation in anterior leads and 1 (5.5%) angina.
Our study indicates that ST depression in a symptom-limited exercise test performed early after an anterior Q-wave acute myocardial infarction is unusual and has low sensitivity (27.8%) to detect multivessel disease. ST elevation is the more common finding in this test (75%) and has no relation with the severity of CAD.
本研究旨在确定早期运动试验检测单纯首次前壁Q波心肌梗死幸存者多支血管病变的可靠性。
在连续100例患者中,64例(年龄55±10岁)纳入研究。34例患者(53.1%)接受了溶栓治疗,根据无创标准,24例患者(37.5%)溶栓成功。所有患者在心肌梗死后11 - 15天进行标准症状限制运动试验,并在72小时内进行冠状动脉造影。
运动试验中,6例(9.3%)患者出现显著ST段压低,48例(75%)出现显著ST段抬高,5例(7.8%)下壁导联ST段压低伴前壁导联ST段抬高,3例(4.6%)出现心绞痛。在18例多支血管病变患者中,5例(27.8%)出现ST段压低,10例(55.5%)出现ST段抬高,1例(5.5%)下壁导联ST段压低伴前壁导联ST段抬高,1例(5.5%)出现心绞痛。
我们的研究表明,在前壁Q波急性心肌梗死后早期进行的症状限制运动试验中,ST段压低不常见,检测多支血管病变的敏感性较低(27.8%)。ST段抬高是该试验中更常见的表现(75%),且与冠心病严重程度无关。