Kovacević S, Knezević M
Veterinary Faculty-Department of Pathological Morphology, University of Belgrade.
Vojnosanit Pregl. 1995 Jan-Feb;52(1):3-8.
The infection Pneumocystis carinii was activated in mice of closely related BALBc/AnNCR, C57BL/6 and DBA/2 strains applying various doses of hydro-cortisone-acetate in combination with hypoprotein or complete food. The males of all investigated strains showed to be more sensitive than the females and the longest survived mice of C57BL/6 strain. The character of pathohistological pulmonary changes varied depending on the duration of survival. The mature cyst forms of Pneumocystis carinii were confirmed in tissue applying GMS and PAP method, and intracystic sporozoite by GMS staining.
在密切相关的BALBc/AnNCR、C57BL/6和DBA/2品系小鼠中，应用不同剂量的醋酸氢化可的松联合低蛋白或全食物，激活卡氏肺孢子虫感染。所有研究品系的雄性小鼠比雌性小鼠更敏感，C57BL/6品系的小鼠存活时间最长。病理组织学肺部变化的特征因存活时间而异。应用GMS和PAP方法在组织中证实了卡氏肺孢子虫的成熟囊肿形式，并通过GMS染色证实了囊内子孢子。
