Burton R C, Armstrong B K
Newcastle Melanoma Unit, Wallsend, New South Wales, Australia.
World J Surg. 1995 May-Jun;19(3):330-3. doi: 10.1007/BF00299151.
During the mid to late 1980s in white populations in Australia, New Zealand, and Scotland, melanoma incidence increased sharply above preceding long-term trends. Most of this increase was in thin melanomas (< 1.50 mm thick), and men were more affected than women. Thick melanomas also generally increased in incidence, particularly in men 65 years or older. Although advancement of the time of diagnosis was a likely factor in the increase in melanoma incidence, the maintenance of new higher incidence levels and the increase in the incidence of thick lesions indicated that earlier diagnosis did not explain most of the increase. Real increases in incidence due to continuation of long-term trends and the increasing diagnosis of a preexisting, nonmetastasizing form of thin melanoma probably explain most of the recent increases in melanoma incidence.
在20世纪80年代中后期，澳大利亚、新西兰和苏格兰的白人人群中，黑色素瘤发病率急剧上升，超过了此前的长期趋势。这种增长大部分发生在薄黑色素瘤（厚度<1.50毫米）中，男性受影响的程度高于女性。厚黑色素瘤的发病率通常也有所上升，尤其是65岁及以上的男性。尽管诊断时间的提前可能是黑色素瘤发病率上升的一个因素，但新的较高发病率水平的维持以及厚病变发病率的增加表明，早期诊断并不能解释大部分的增长。由于长期趋势的延续以及对一种先前存在的、非转移性薄黑色素瘤形式的诊断增加导致的实际发病率上升，可能解释了近期黑色素瘤发病率增加的大部分原因。
