Linares M, Cerveró A, Colomina P, Pastor E, López A, Pérez A, Perella M, Carbonell F
Department of Hematology, Hospital General Universitario de Valencia, Spain.
Acta Haematol. 1995;93(2-4):80-2. doi: 10.1159/000204116.
From a group of 118 patients with chronic idiopathic thrombocytopenic purpura (ITP), 43 were older than 60 years at diagnosis. In this report, we describe the clinical evolution and therapeutic response in young and old patients. The overal rate of hemorrhagic manifestations was similar in the two age groups, but a greater risk for severe bleeding was observed in elderly patients. There were no significant differences between old and young patients in response to steroids. In none of our patients was mortality associated with bleeding or side effects of the treatment. In conclusion, we have observed a more benign clinical course in elderly patients with chronic ITP as compared to previous reports.
在一组118例慢性特发性血小板减少性紫癜（ITP）患者中，43例在诊断时年龄超过60岁。在本报告中，我们描述了年轻和老年患者的临床病程及治疗反应。两个年龄组的出血表现总体发生率相似，但老年患者发生严重出血的风险更高。老年和年轻患者对类固醇的反应无显著差异。在我们的患者中，无一例死亡与出血或治疗副作用相关。总之，与既往报告相比，我们观察到老年慢性ITP患者的临床病程更为良性。
