Alvarez O A, Maples J A, Tio F O, Lee M
Department of Medicine, University of Texas Health Science Center, San Antonio, USA.
Am J Gastroenterol. 1995 Aug;90(8):1350-1.
Cokeromyces recurvatus, a sporangiola-forming dimorphic fungus, is a rare cause of urogenital infection in humans. We report here a case of severe watery diarrhea due to C. recurvatus, which was treated successfully with high-dose oral nystatin therapy. We speculate that our patient was probably predisposed to infections due to opportunistic organisms, such as C. recurvatus, because of post-transplantation immunosuppression. To our knowledge, our patient represents the first documented case of diarrhea due to C. recurvatus in man, and this case highlights the potential pathogenic capability of this opportunistic organism in immunosuppressed patients.
弯孢科克霉，一种形成孢子囊梗的双态真菌，是人类泌尿生殖系统感染的罕见病因。我们在此报告一例由弯孢科克霉引起的严重水样腹泻病例，该病例通过大剂量口服制霉菌素治疗成功治愈。我们推测，由于移植后免疫抑制，我们的患者可能易受诸如弯孢科克霉等机会性生物体感染。据我们所知，我们的患者是文献记载的首例人类因弯孢科克霉引起腹泻的病例，该病例凸显了这种机会性生物体在免疫抑制患者中的潜在致病能力。
