大鼠子宫雌激素受体的泛素化：对雌二醇的依赖性。
Ubiquitination of the rat uterine estrogen receptor: dependence on estradiol.
作者信息
Nirmala P B, Thampan R V
机构信息
Department of Biochemistry, School of Life Sciences, University of Hyderabad, India.
出版信息
Biochem Biophys Res Commun. 1995 Aug 4;213(1):24-31. doi: 10.1006/bbrc.1995.2093.
PMID:7639742
Abstract
Using polyclonal antibodies against estrogen receptor and ubiquitin, the ubiquitination of the estrogen receptor has been demonstrated in both in vitro and in vivo conditions. The ubiquitination of the estrogen receptor is estradiol specific and is enhanced by estradiol. Estrogen withdrawal is associated with decreased ubiquitination of the estrogen receptor.
摘要
使用针对雌激素受体和泛素的多克隆抗体，已在体外和体内条件下证实了雌激素受体的泛素化。雌激素受体的泛素化具有雌二醇特异性，并且会被雌二醇增强。雌激素撤退与雌激素受体泛素化减少有关。
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