健康维护组织中患者手部、髋部和膝部症状性骨关节炎的发病率。

Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization.

作者信息

Oliveria S A, Felson D T, Reed J I, Cirillo P A, Walker A M

机构信息

Strang Cancer Prevention Center, New York, NY 10021, USA.

出版信息

Arthritis Rheum. 1995 Aug;38(8):1134-41. doi: 10.1002/art.1780380817.

DOI:10.1002/art.1780380817

PMID:7639811

Abstract

OBJECTIVE

To quantify the incidence of symptomatic hand, hip, and knee osteoarthritis (OA) among members of the Fallon Community Health Plan, a health maintenance organization located in central Massachusetts.

METHODS

Incident OA was defined as the first evidence of OA by radiography (grade > or = 2 on the Kellgren-Lawrence scale of 0-4) plus joint symptoms at the time the radiograph was obtained or up to 1 year before the radiograph was obtained.

RESULTS

The age- and sex-standardized incidence rate for hand OA was 100/100,000 person-years (95% confidence interval [95% CI] 86, 115), for hip OA 88/100,000 person-years (95% CI 75, 101), and for knee OA 240/100,000 person-years (95% CI 218, 262). The incidence of hand, hip, and knee OA increased with age, and women had higher rates than men, especially after age 50. A leveling off or decline occurred for both groups around the age of 80.

CONCLUSION

In a large study of symptomatic OA we observed incidence rates that increased with age. In women ages 70-89, the incidence of knee OA approached 1% per year.

摘要

目的

量化位于马萨诸塞州中部的一家健康维护组织——法伦社区健康计划成员中手部、髋部和膝部症状性骨关节炎（OA）的发病率。

方法

新发OA定义为通过X线摄影显示OA的首个证据（在0 - 4级的凯尔格伦 - 劳伦斯量表上分级≥2级）加上在获得X线片时或在获得X线片前1年内出现的关节症状。

结果

手部OA的年龄和性别标准化发病率为每100,000人年100例（95%置信区间[95%CI]86, 115），髋部OA为每100,000人年88例（95%CI 75, 101），膝部OA为每100,000人年240例（95%CI 218, 262）。手部、髋部和膝部OA的发病率随年龄增加，女性发病率高于男性，尤其是在50岁以后。两组在80岁左右发病率趋于平稳或下降。