Boman F, Champigneulle J, Boccon-Gibod L, Merlin J L, De Miscault G, Schmitt C, Sommelet D, Floquet J
Service d'Anatomie et de Cytologie Pathologiques, C.H.U. de Brabois, Vandoeuvre.
Ann Pathol. 1995;15(3):207-10.
Pulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor, plasma cell granuloma) was reported most often as a single peripheral mass, successfully cured by surgery. A 14-year-old girl presented with a large left pulmonary mass involving and obliterating the main bronchus; there were angioinvasion and infiltration of mediastinum, hilar lymph nodes and pleura. Multiple, often tiny nodules were seen in the right lung. At microscopic examination, there were lymphocytic and plasmacytic infiltrates and borderline myofibroblastic proliferation with focal nuclear anaplasia. Smaller lesions were similar to organizing pneumonia. Disease was progressive in the remaining right lung after surgical resection and a two-month treatment with corticoids. The patient was then treated with chemotherapy. She was alive and well (twenty-month follow-up).
肺炎性肌纤维母细胞瘤（炎性假瘤、浆细胞性肉芽肿）最常被报道为单个周围型肿块，手术可成功治愈。一名14岁女孩表现为左肺巨大肿块，累及并阻塞主支气管；存在血管侵犯以及纵隔、肺门淋巴结和胸膜浸润。右肺可见多个通常较小的结节。显微镜检查显示有淋巴细胞和浆细胞浸润以及边界性肌纤维母细胞增生，并伴有局灶性核间变。较小的病变类似于机化性肺炎。手术切除及使用皮质类固醇治疗两个月后，右肺剩余部分的病情仍在进展。随后该患者接受了化疗。她存活良好（随访20个月）。
