Răşinaru A, Olinici C D, Blaga M L
Institute of Oncology, Cluj-Napoca, Romania.
Rom J Morphol Embryol. 1994 Jan-Jun;40(1-2):7-10.
The authors have studied the nucleolar organizer regions (AgNORs) (which reflect the cell kinetic activity) in the in situ and invasive components of breast cancers. The mean number of AgNORs/nucleus was 4.18 (s.d.: 1.35) in the in situ compartments and 5.41 (s.d.: 1.90) in invasive areas. The difference between these two groups is statistically significant. The higher proliferative activity in the infiltrating component might be due to the interaction between epithelial cells and the supporting stroma.
作者研究了乳腺癌原位成分和浸润成分中的核仁组织区(AgNORs)(反映细胞动力学活性)。原位区AgNORs/细胞核的平均数量为4.18(标准差:1.35),浸润区为5.41(标准差:1.90)。这两组之间的差异具有统计学意义。浸润成分中较高的增殖活性可能归因于上皮细胞与支持性基质之间的相互作用。