Vassa N, Nolph K D, Prowant B F, Moore H L, Khanna R, Twardowski Z J
Division of Nephrology, University of Missouri Health Sciences Center, Dalton Research Center, Columbia 65212, USA.
ASAIO J. 1995 Apr-Jun;41(2):194-7.
Dialysate and blood leukocyte counts were measured during 130 episodes of peritonitis in 91 hospitalized patients on long-term peritoneal dialysis (CPD). The authors found that the blood/dialysate leukocyte count can be less than 1.0, and this is usually the case when dialysate leukocyte count exceeds 20,000/mm3. Dialysate leukocyte removal in a single 2 L drain bag can approach the leukocyte number in the entire circulating blood volume. Daily drainage can remove leukocytes in amounts exceeding the blood leukocyte pool 2 to 3 fold. The observed blood leukocyte counts throughout a range of 2,700 to 10,000 at dialysate leukocyte counts greater than 20,000 per mm3 may reflect: 1) leukocyte removal approaching maximum bone marrow output of leukocytes, and/or 2) increasing microcirculatory margination of leukocytes in those episodes of peritonitis associated with very high dialysate leukocyte counts.
对91例长期持续性腹膜透析（CPD）住院患者的130次腹膜炎发作期间的透析液和血液白细胞计数进行了测量。作者发现血液/透析液白细胞计数可能低于1.0，当透析液白细胞计数超过20,000/mm³时通常就是这种情况。在一个2L的引流袋中单次清除的透析液白细胞数量可接近全循环血量中的白细胞数量。每日引流可清除的白细胞数量超过血液白细胞池的2至3倍。在透析液白细胞计数大于20,000/mm³的情况下，观察到的血液白细胞计数在2700至10,000范围内，这可能反映了：1）白细胞清除接近骨髓白细胞的最大输出量，和/或2）在那些与非常高的透析液白细胞计数相关的腹膜炎发作中，白细胞的微循环边缘化增加。
