Ferguson J M, Gillespie I N, Chalmers N, Elton R A, Hargreave T B
Department of Radiology, Royal Infirmary of Edinburgh, UK.
Br J Radiol. 1995 Jul;68(811):700-3. doi: 10.1259/0007-1285-68-811-700.
Clinical and sub-clinical varicoceles are associated with infertility and abnormal sperm parameters. Percutaneous embolization is a minimally invasive, safe, outpatient method of treatment which is cost effective in comparison to surgery. This study is a retrospective review of embolization of the spermatic vein using stainless steel occluding spring coils, performed in 116 males from two infertility clinics. Follow-up results were complete in 87 patients of which 79 (91%) were successful both technically and clinically and all had sperm analysis performed both before and within 2 years after embolization. There was a highly significant increase in motility (mean 35% before, mean 46% after, p < 0.001). Sperm density showed a trend towards improvement, but only p < 0.10, and there was no significant change in semen volume or morphology. The partners of 29 men (33%) became pregnant in a total of 241 years of follow-up.
临床型和亚临床型精索静脉曲张与不育症及异常精子参数相关。经皮栓塞术是一种微创、安全的门诊治疗方法，与手术相比具有成本效益。本研究是对来自两家不育症诊所的116名男性使用不锈钢闭塞弹簧圈进行精索静脉栓塞术的回顾性分析。87例患者随访结果完整，其中79例（91%）在技术和临床方面均成功，并且所有患者在栓塞术前及栓塞术后2年内均进行了精子分析。精子活力显著提高（术前平均为35%，术后平均为46%，p<0.001）。精子密度有改善趋势，但p<0.10，精液量和形态无显著变化。在总共241年的随访中，29名男性（33%）的伴侣怀孕。
