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在脊髓损伤动物模型中,使用经皮电极进行膀胱直接刺激并监测容量阻抗。

Direct bladder stimulation with percutaneous electrodes and impedance monitoring of volume in an SCI animal model.

作者信息

Walter J S, Zaszczurynski P, Cai W, Wheeler J S, Riedy L, Scarpine V E

机构信息

Rehabilitation Research and Development Center, Hines VA Hospital, IL 60141, USA.

出版信息

J Spinal Cord Med. 1995 Apr;18(2):98-102. doi: 10.1080/10790268.1995.11719386.

DOI:10.1080/10790268.1995.11719386
PMID:7640980
Abstract

Bladder responses to percutaneous electrodes were investigated with stimulation in three male spinal cats. The animals had been spinalized (T1 level lesion) 10 weeks prior to these studies and had been instrumented with chronic bladder had been spinalized (T1 level lesion) 10 weeks prior to these studies and had been instrumented with chronic bladder wall electrodes and suprapubic bladder catheters for filling and pressure recording. percutaneous stimulation in tethered animals was conducted wit hook electrodes inserted with a needle in the abdomen bilaterally adjacent to the bladder trigone. Stimulation was conducted with 40 Hz pulse trains of 10 to 30 mA for three seconds. Stimulation with both percutaneous and chronic electrodes induced high bladder pressures and voiding. In addition, with chronically implanted electrodes, impedance monitoring of bladder volume was found to be an effective recording technique.

摘要

在三只雄性脊髓猫中,通过刺激研究了膀胱对经皮电极的反应。这些动物在这些研究前10周已进行脊髓横断(T1水平损伤),并已植入慢性膀胱壁电极和耻骨上膀胱导管用于膀胱充盈和压力记录。在束缚动物中,经皮刺激是通过将钩状电极经针双侧插入膀胱三角区附近的腹部来进行的。刺激采用40Hz的脉冲串,电流为10至30mA,持续三秒。经皮电极和慢性电极刺激均诱发了高膀胱压力和排尿。此外,发现使用慢性植入电极时,膀胱容量的阻抗监测是一种有效的记录技术。

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Direct bladder stimulation with percutaneous electrodes and impedance monitoring of volume in an SCI animal model.在脊髓损伤动物模型中,使用经皮电极进行膀胱直接刺激并监测容量阻抗。
J Spinal Cord Med. 1995 Apr;18(2):98-102. doi: 10.1080/10790268.1995.11719386.
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引用本文的文献

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Can we improve techniques and patients' selection for nerve stimulation suitable for lower urinary tract dysfunctions? ICI-RS 2023.我们能否改进适合下尿路功能障碍的神经刺激技术和患者选择?ICI-RS 2023.
Neurourol Urodyn. 2024 Aug;43(6):1420-1430. doi: 10.1002/nau.25346. Epub 2023 Dec 4.
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Assessing Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury: Animal Models in Preclinical Neuro-Urology Research.脊髓损伤后神经源性下尿路功能障碍的评估:临床前神经泌尿学研究中的动物模型
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