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影响夫精人工授精妊娠率的精液分析参数。

Parameters of semen analysis affecting the pregnancy rate of artificial insemination with husband's spermatozoa.

作者信息

Huang H Y, Chang M Y, Lee C L, Lai Y M, Chang S Y, Soong Y K

机构信息

Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.

出版信息

Changgeng Yi Xue Za Zhi. 1995 Jun;18(2):109-14.

PMID:7641101
Abstract

The efficacy of intrauterine insemination with husband's semen (AIH) is well established for some types of infertility. Results that had been reported previously were Dwing difficult to assess owing to the low number of patients or treatment cycles as well as an inadequate definition of the indications in most cases. In this study, we report our experience with intrauterine insemination (IUI) using post-treated sperm suspension from husband's semen in the treatment of infertility. A total of 328 treatment cycles were completed from January to December in 1991. The indications for AIH/IUI were male infertility (130 cycles), unexplained infertility (87 cycles), sex selection (72 cycles) and anovulatory disorder (39 cycles). Sixty-eight pregnancies were achieved. The clinical usefulness of AIH/IUI with or without concomitant hMG regimens were established according to diagnostic subgroups. In our results, the cycle fecundity of pregnancy was higher in patients with ovulatory disturbance. The importance of sperm motility confirmed by our results that have compared by the serial sperm parameters. The motile sperm count may appear to be a highly consistent parameter that serves as a sensitive indicator of sperm function and correlation of successful pregnancy in our results. In conclusion, this study indicates that AIH with controlled ovarian hyperstimulation can result in higher viable pregnancy rate, and it is also a non-invasive and relatively easy procedure. We believe that this is a transient useful method for the treatment of non-organic infertility, prior to any attempt of aggressive assisted reproductive procedures.

摘要

丈夫精液宫腔内人工授精(AIH)对某些类型的不孕症疗效已得到充分证实。由于患者或治疗周期数量较少,以及在大多数情况下适应症定义不充分,先前报道的结果难以评估。在本研究中,我们报告了使用丈夫精液经处理后的精子悬液进行宫腔内人工授精(IUI)治疗不孕症的经验。1991年1月至12月共完成了328个治疗周期。AIH/IUI的适应症包括男性不育(130个周期)丶不明原因不育(87个周期)丶性别选择(72个周期)和无排卵障碍(39个周期)。共实现了68例妊娠。根据诊断亚组确定了AIH/IUI联合或不联合hMG方案的临床实用性。在我们的结果中,排卵障碍患者的妊娠周期受孕率更高。通过我们的结果比较系列精子参数证实了精子活力的重要性。在我们的结果中,活动精子计数似乎是一个高度一致的参数,可作为精子功能的敏感指标和成功妊娠的相关性指标。总之,本研究表明,控制性卵巢过度刺激的AIH可导致更高的活产妊娠率,并且这也是一种非侵入性且相对简单的程序。我们认为,在尝试任何积极的辅助生殖程序之前,这是一种治疗非器质性不孕症的暂时有用方法。

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Artificial insemination with husband's semen: prognostic factors.丈夫精液人工授精:预后因素
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