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在有视觉先兆的偏头痛患者中,检测目标物相对于背景光栅的阈值提示存在视觉功能障碍,但无视觉先兆的偏头痛患者则不然。

Thresholds for detection of a target against a background grating suggest visual dysfunction in migraine with aura but not migraine without aura.

作者信息

Chronicle E P, Wilkins A J, Coleston D M

机构信息

Department of Psychology, Lancaster University, UK.

出版信息

Cephalalgia. 1995 Apr;15(2):117-22. doi: 10.1046/j.1468-2982.1995.015002117.x.

DOI:10.1046/j.1468-2982.1995.015002117.x
PMID:7641245
Abstract

Square-wave gratings with particular spatial characteristics induce visual illusions. Patients with migraine are particularly susceptible to these illusions and report discomfort. Their discomfort tends to be greater when the gratings are illuminated by red light, a tendency not shown by controls. Gratings that induce illusions have been found to impair the recognition of optically superimposed targets in headache-free control subjects. We measured the impairment of target detection under illuminants of various chromaticities in migraineurs with and without aura and in matched controls. Migraineurs with aura had significantly higher thresholds for target detection than either migraineurs without aura or controls; in addition, the effect of chromaticity was slightly more pronounced in both migraine groups than in the control group. These findings are consistent with a recent suggestion that migraine with aura might give rise to subclinical damage to the primary visual cortex.

摘要

具有特定空间特征的方波光栅会引发视觉错觉。偏头痛患者对这些错觉尤为敏感,并会感到不适。当光栅由红光照明时,他们的不适感往往更强,而对照组则没有这种倾向。已发现引发错觉的光栅会损害无头痛对照组受试者对光学叠加目标的识别。我们测量了有先兆和无先兆偏头痛患者以及匹配对照组在不同色度光源下目标检测的受损情况。有先兆偏头痛患者的目标检测阈值显著高于无先兆偏头痛患者或对照组;此外,两个偏头痛组中色度的影响都比对照组略为明显。这些发现与最近的一项观点一致,即有先兆偏头痛可能会对初级视觉皮层造成亚临床损伤。

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