Schaffer J L, Dark M, Itzkan I, Albagli D, Perelman L, von Rosenberg C, Feld M S
Laboratory for the Study of Skeletal Disorders and Rehabilitation, Children's Hospital, Boston, MA, USA.
Clin Orthop Relat Res. 1995 Jan(310):30-6.
A new experimental technique was developed to study short-pulsed laser ablation of biologic tissues (human meniscus and bovine tibial bone), water, and acrylic. The experimental technique was based on interferometric monitoring of the motion of the tissue surface to measure its laser-induced expansion after irradiation. The thermoelastic expansion of these materials after laser irradiation under subablation threshold was examined to determine its role in the initiation of ablation. The experimentally observed surface expansion of cortical bone and acrylic was in agreement with theoretical predictions. The movement of meniscal tissue was similar to that shown by water. The latter 2 materials showed additional features consistent with the growth and collapse of cavitation bubbles. The exact role of cavitation in the irradiation of meniscal tissue by laser light remains unknown, but may represent a clinically important mode of tissue ablation and postirradiation trauma.
一种新的实验技术被开发出来，用于研究短脉冲激光对生物组织（人半月板和牛胫骨）、水和丙烯酸树脂的消融。该实验技术基于对组织表面运动的干涉测量，以测量其在照射后的激光诱导膨胀。研究了这些材料在亚消融阈值下激光照射后的热弹性膨胀，以确定其在消融起始中的作用。实验观察到的皮质骨和丙烯酸树脂的表面膨胀与理论预测一致。半月板组织的运动与水的运动相似。后两种材料表现出与空化气泡的生长和坍塌相一致的其他特征。空化在激光照射半月板组织中的具体作用尚不清楚，但可能代表一种临床上重要的组织消融和照射后创伤模式。
