Hart Y M, Shorvon S D
Institute of Neurology, Queen Square, London, United Kingdom.
Epilepsy Res. 1995 May;21(1):43-9. doi: 10.1016/0920-1211(95)00007-w.
The study is a community-based study carried out in the UK to determine the characteristics of patients receiving treatment for epilepsy, with particular reference to the duration, nature and severity of epilepsy. 119 participating general practitioners distributed questionnaires to 2528 patients taking medication for epilepsy. Information requested included the age and sex distribution of the patients, seizure type, duration of epilepsy and frequency of seizures, employment status of the patients, and state benefits received. 1628 patients replied. The prevalence of people receiving treatment for epilepsy was estimated at 4.5/1000. Fourteen per cent were under the age of 20 years and 23% were aged 60 or more. Seventy per cent had had epilepsy for at least 5 years, while 8% had been diagnosed in the previous year. Fifty-three per cent had had one or more seizures in the year prior to the survey, and 20% had seizures at least monthly on average. Most patients had seizures of partial origin. The rate of unemployment and receipt of social security benefits was higher than in the general population. The study indicates that the majority of patients receiving treatment for epilepsy in the community have long-standing epilepsy, often intractable to medical treatment, and associated with considerable social handicap. Health care planning should take this into account.
该研究是在英国开展的一项基于社区的研究,旨在确定接受癫痫治疗患者的特征,尤其涉及癫痫的病程、性质和严重程度。119名参与研究的全科医生向2528名正在服用抗癫痫药物的患者发放了问卷。所要求的信息包括患者的年龄和性别分布、发作类型、癫痫病程和发作频率、患者的就业状况以及领取的国家福利。1628名患者进行了回复。接受癫痫治疗的人群患病率估计为4.5/1000。14%的患者年龄在20岁以下,23%的患者年龄在60岁及以上。70%的患者癫痫病程至少5年,而8%的患者是在前一年确诊的。53%的患者在调查前一年有过一次或多次发作,20%的患者平均每月至少发作一次。大多数患者的发作起源于局部。失业和领取社会保障福利的比例高于普通人群。该研究表明,社区中接受癫痫治疗的大多数患者患有长期癫痫,通常难以通过药物治疗,且伴有相当严重的社会障碍。医疗保健规划应考虑到这一点。