Biggeri A, Lagazio C
Dipartimento Statistico, Universitá di Firenze.
Epidemiol Prev. 1995 Jun;19(63):190-2.
This paper discusses the analysis of the disease risk as function of distance from prespecified exposure sources. Instead of the usual ecological framework, the proposed model is based on individual data and includes the major individual risks factors as covariates. The risk due to environmental exposure is modelled using excess relative risk as effect measure, while the effect of individual risk factors is modelled using relative risk. A case-control design is proposed to fit this model and to obtain effect estimates.
本文讨论了将疾病风险分析作为距预先指定暴露源距离的函数。所提出的模型并非基于通常的生态框架，而是基于个体数据，并将主要的个体风险因素作为协变量纳入。环境暴露导致的风险使用超额相对风险作为效应量进行建模，而个体风险因素的效应则使用相对风险进行建模。本文提出了一种病例对照设计来拟合该模型并获得效应估计值。
