[放射治疗对控制结直肠癌是否必要？]

[Is radiotherapy necessary in the control of colorectal cancer?].

作者信息

Molina Esquivel J, Vargas Sandoval G, Rodríguez del Rincón E, Velázquez López J

机构信息

Departamento de Radioterapia (Sevicio de Oncología), Hospital 20 de Noviembre del Instituto de Seguridad Social al Servicio de los Trabajadores del Estado, México, D.F.

出版信息

Ginecol Obstet Mex. 1995 Jun;63:256-61.

PMID:7642153

Abstract

Between 1966 and 1983 we selected 209 patients with colorectal adenocarcinomas, stage B (14%) and C (86%) of Dukes, treated with convenient surgery in 100% of cases, 5-fluorouracil in 85% and postoperative radiotherapy with telecobalt in 46.41% of cases, doses of 5000 to 5500 cGy in 25 to 30 fractions. The results at five years postsurgery were: colon patients who received radiotherapy obtained a survival rate of 34 months versus 17 months for those who did not receive radiotherapy; rectum patients who received radiotherapy survival rate of 20 months versus 26 months for those who did not received. Local recurrences in patients who received radiotherapy were 9.30% for carcinomas of the colon and 11.53% for those with cancer of the rectum, and in patients who did not received radiotherapy local recurrences were 22.22% for those with cancer of the colon and 37.83% for those with cancer of the rectum.

摘要

1966年至1983年间，我们选取了209例结肠直肠癌患者，其中杜克B期（14%）和C期（86%），所有病例均采用简便手术治疗，85%的病例使用5-氟尿嘧啶，46.41%的病例采用钴远距离术后放疗，剂量为5000至5500厘戈瑞，分25至30次照射。术后五年的结果如下：接受放疗的结肠癌患者生存率为34个月，未接受放疗的患者为17个月；接受放疗的直肠癌患者生存率为20个月，未接受放疗的患者为26个月。接受放疗的患者中，结肠癌局部复发率为9.30%，直肠癌为11.53%；未接受放疗的患者中，结肠癌局部复发率为22.22%，直肠癌为37.83%。