McNeil R G, Ritter R C, Wang B, Lawson M A, Gillies G T, Wika K G, Quate E G, Howard M A, Grady M S
Stereotaxis, Inc., Menlo Park, CA 94025, USA.
IEEE Trans Biomed Eng. 1995 Aug;42(8):793-801. doi: 10.1109/10.398640.
A helmet with a roughly cubic array of six super-conducting coils is used to apply force on a small permanent magnet pellet in brain or in brain phantom material. This apparatus, called the Magnetic Stereotaxis System, will be used to deliver drugs and other therapies directly into deep brain tissues, under control of a computer and fluoroscopic imaging system. This paper considers only the force application aspects of the instrument. The primary design features of the helmet and power supply controls are presented, along with field plot data and single-axis motion results. The field plot data show that agreement with the finite-element iron-free field calculations is sufficiently high (> 1%) for the instrument. These preliminary motion data indicate accuracy better than 2 mm for the impulsive pellet motion, even though the visual position observations had significantly greater error than the completed imaging system will have. The companion paper will take up analysis of the control aspects of the motion, and our recent solutions to difficulties found in the experimental work described here.
一种带有六个超导线圈大致呈立方体阵列的头盔,用于对置于大脑或脑模型材料中的小永磁体小球施加力。这种被称为磁立体定位系统的装置,将在计算机和荧光成像系统的控制下,用于将药物和其他治疗手段直接输送到深部脑组织。本文仅考虑该仪器的力施加方面。介绍了头盔和电源控制的主要设计特点,以及场图数据和单轴运动结果。场图数据表明,该仪器与无铁有限元场计算结果的一致性足够高(>1%)。这些初步运动数据表明,即使视觉位置观测的误差明显大于完整成像系统的误差,脉冲小球运动的精度仍优于2毫米。配套论文将分析运动控制方面以及我们最近针对此处所述实验工作中发现的困难所采取的解决方案。