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人和猪肠道螺旋体对1日龄无特定病原体雏鸡的致病性:肠道螺旋体病的动物模型

Pathogenicity of human and porcine intestinal spirochetes in one-day-old specific-pathogen-free chicks: an animal model of intestinal spirochetosis.

作者信息

Trott D J, McLaren A J, Hampson D J

机构信息

School of Veterinary Studies, Murdoch University, Australia.

出版信息

Infect Immun. 1995 Sep;63(9):3705-10. doi: 10.1128/iai.63.9.3705-3710.1995.

Abstract

One-day-old chicks were infected orally with two strains of weakly hemolytic spirochetes isolated from a human and a pig with intestinal spirochetosis. These spirochetosis both colonized birds, attached end-on to their cecal enterocytes, induced watery diarrhea, and significantly depressed growth rates. Cultures of Serpulina innocens failed to colonize the chicks.

摘要

一日龄雏鸡经口感染了从患有肠道螺旋体病的人和猪身上分离出的两株弱溶血螺旋体。这两种螺旋体病均在禽类中定殖,以端部附着于盲肠肠上皮细胞,引发水样腹泻,并显著降低生长速率。无害蛇形螺旋体培养物未能在雏鸡中定殖。

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