Mackenzie T B, Ristvedt S L, Christenson G A, Lebow A S, Mitchell J E
Department of Psychiatry, University of Minnesota, Minneapolis, USA.
J Behav Ther Exp Psychiatry. 1995 Mar;26(1):9-16. doi: 10.1016/0005-7916(94)00074-v.
Subjects with obsessive compulsive disorder, bulimia nervosa, or trichotillomania selected cues which elicited or worsened their symptoms from a 339 item list. Principal components analysis suggested a four-component solution. Each disorder was significantly associated with one of these components. Diagnostic assignment based on component scores yielded 85% correct classification. The diagnostic groups did not differ on a negative feeling state component. The results indicate that both disorder-specific and generic components exist. This approach has potential for defining clinical subtypes, studying the interaction of feeling states and environmental cues in evoking symptoms, and designing treatment strategies.
患有强迫症、神经性贪食症或拔毛癖的受试者从一份339项的列表中选择了引发或加重其症状的线索。主成分分析提出了一个四成分的解决方案。每种障碍都与其中一个成分显著相关。基于成分得分的诊断分类得出了85%的正确分类率。诊断组在消极情绪状态成分上没有差异。结果表明,既存在特定于障碍的成分,也存在通用成分。这种方法在定义临床亚型、研究情绪状态与环境线索在引发症状中的相互作用以及设计治疗策略方面具有潜力。