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[复发性短暂抑郁]

[Recurrent brief depression].

作者信息

Amore M, Ricci M, Giorgetti G

机构信息

Istituto di Psichiatria P. Ottonello, Università degli Studi, Bologna.

出版信息

Minerva Psichiatr. 1995 Jun;36(2):83-9.

PMID:7643738
Abstract

The initial conception of manic depressive illness by Kraepelin included short and mild depressive and hypomanic states in the nosologic category of affective illness. The concept of recurrent brief depression was further confirmed in recent community and general practice studies. The diagnostic criteria for recurrent brief depression requires the presence of at least five of nine depressive symptoms analogous to the symptoms of major depression, yet a duration of less than two weeks (in general 1 to 3 days), a recurrence of at least 12 times a year, and the evidence of work impairment. The 1-year prevalence in the general population is about 5% and the lifetime prevalence 16%. Recurrent brief depression may develop into major depression and vice versa in about the same percentage of cases. Patients with combined major and recurrent brief depression are more severely affected, have a higher suicide attempt rate, and have an increased frequency of treatment--seeking than patients with only one condition. Recurrent brief depression is typically characterized by monthly occurring short-lived depressive episodes, with an erratic, relapsing and chronic course and significant suicide risk. The duration of these episodes in clinical samples was of 3-5 days on average, with a medium number of episode a year of 20. The onset of episodes is sudden and patients progress rapidly to the severe levels of depression. Resolution of the symptoms also tends to be rapid. The suddeness of the episodes may contribute to the relationship reported with suicidal behaviour. This is a disabling illness because of the frequency with which the episodes recur reported as erratic "irregularly regular".(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

克雷佩林对躁郁症的最初概念包括在情感性疾病的分类学范畴中有短暂且轻度的抑郁和轻躁狂状态。近期社区和全科医学研究进一步证实了复发性短暂抑郁的概念。复发性短暂抑郁的诊断标准要求存在至少九种与重度抑郁症状类似的抑郁症状中的五种,但持续时间少于两周(一般为1至3天),每年复发至少12次,并有工作受损的证据。普通人群中的1年患病率约为5%,终生患病率为16%。复发性短暂抑郁在大约相同比例的病例中可能发展为重度抑郁,反之亦然。合并有重度抑郁和复发性短暂抑郁的患者受影响更严重,自杀未遂率更高,且寻求治疗的频率比仅患一种疾病的患者更高。复发性短暂抑郁的典型特征是每月出现短暂的抑郁发作,病程不稳定、复发且呈慢性,并有显著的自杀风险。临床样本中这些发作的持续时间平均为3至5天,每年发作次数平均为20次。发作起病突然,患者迅速发展到重度抑郁水平。症状缓解也往往很快。发作的突然性可能导致与自杀行为相关的报道。这是一种致残性疾病,因为发作频繁,且发作时间不稳定,呈“不规则的规律”。(摘要截选至250字)

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