Gilliam F, Wyllie E
Section of Epilepsy and Clinical Neurophysiology, Cleveland Clinic Foundation, OH, USA.
Neurology. 1995 Aug;45(8):1619-21. doi: 10.1212/wnl.45.8.1619.
We studied seven consecutive patients who experienced amaurosis as a prominent feature of their seizures. The mean age of seizure onset was 4 years. Six patients had MRI abnormalities including ischemic, traumatic, and space-occupying lesions, with five limited to the parietal-occipital region. Six patients had unilateral, posterior interictal spike and slow wave complexes. Four patients experienced severe postictal headache and nausea. Absence of a family history of seizures distinguished the patients with MRI lesions from previously presented series of benign occipital lobe epilepsy. We conclude that the constellation of ictal amaurosis, occipital paroxysms, and postictal migrainous symptoms does not necessarily signify a benign, nonlesional epilepsy; MRI is recommended for such patients without a family history of similar seizures.
我们研究了连续7例以黑矇作为癫痫发作突出特征的患者。癫痫发作的平均起病年龄为4岁。6例患者存在MRI异常，包括缺血性、创伤性和占位性病变，其中5例局限于顶枕区。6例患者出现单侧发作间期后部尖波和慢波复合波。4例患者发作后出现严重头痛和恶心。无癫痫家族史可将有MRI病变的患者与先前报道的一系列良性枕叶癫痫患者区分开来。我们得出结论，发作性黑矇、枕叶阵发和发作后偏头痛样症状并不一定意味着是良性、无病变的癫痫；对于无类似癫痫家族史的此类患者，建议进行MRI检查。
