Mendola P, Marshall J, Graham S, Laughlin R H, Freudenheim J L
Department of Social and Preventive Medicine, State University of New York at Buffalo 14214, USA.
Nutr Cancer. 1995;23(2):161-9. doi: 10.1080/01635589509514372.
Dietary fat intake has been associated with the development of chronic diseases, including heart disease and cancer, in human populations; however, associations demonstrated between disease and fat intake may be confounded by related dietary factors. Therefore, description of the correlates of fat intake in free-living adults may help identify important confounders independent of disease status. In a population of 863 women and 538 men between the ages of 50 and 85 randomly selected from two counties in western New York, we found that most nutrients were correlated with grams of total fat intake including protein, carbohydrates, cholesterol, dietary fiber, retinol, iron, and calcium. Carbohydrates and dietary fiber were not related to the concentration of fat in the diet (% of energy from fat). Alcohol intake was negatively associated with fat concentration for men but not for women. Particularly important for the study of cancers, the antioxidants carotene and ascorbic acid were negatively associated with fat concentration in the diet.
在人群中,膳食脂肪摄入与包括心脏病和癌症在内的慢性疾病的发生有关;然而,疾病与脂肪摄入之间显示出的关联可能会被相关的饮食因素所混淆。因此,描述自由生活的成年人脂肪摄入的相关因素可能有助于识别独立于疾病状态的重要混杂因素。在从纽约西部两个县随机选取的863名年龄在50至85岁之间的女性和538名男性人群中,我们发现大多数营养素与总脂肪摄入量(克数)相关,包括蛋白质、碳水化合物、胆固醇、膳食纤维、视黄醇、铁和钙。碳水化合物和膳食纤维与饮食中脂肪的浓度(来自脂肪的能量百分比)无关。酒精摄入量与男性的脂肪浓度呈负相关,但与女性无关。对于癌症研究尤为重要的是,抗氧化剂胡萝卜素和抗坏血酸与饮食中脂肪的浓度呈负相关。