淋巴瘤患者中的海蓝色组织细胞。

Sea-blue histiocytes in a patient with lymphoma.

作者信息

Mason B A, Bowers G R, Guccion J G, Schechter G P

出版信息

Am J Med. 1978 Mar;64(3):515-8. doi: 10.1016/0002-9343(78)90245-0.

Abstract

A middle-aged man with lymphocytic lymphoma had numerous sea-blue histiocytes in his bone marrow, splenomegaly and thrombocytopenia. Thus, his illness mimicked that of patients with the primary syndrome of the sea-blue histiocyte. However, the paucity of sea-blue histiocytes in his spleen, the absence of neurologic disease, his age and the ultrastructure of his abnormal histiocytes were all evidence for the presence of the acquired syndrome. The pathogenesis of sea-blue histiocytosis and the relationship between acquired cases and the primary syndrome are discussed.

摘要

一名患有淋巴细胞性淋巴瘤的中年男性，其骨髓中有大量海蓝色组织细胞，伴有脾肿大和血小板减少。因此，他的病情类似于海蓝色组织细胞原发性综合征患者的病情。然而，他脾脏中海蓝色组织细胞数量较少、无神经系统疾病、他的年龄以及异常组织细胞的超微结构均表明存在获得性综合征。本文讨论了海蓝色组织细胞增多症的发病机制以及获得性病例与原发性综合征之间的关系。