Fiirgaard B, Madsen H H, Svare U, Skjødt T, Zeeberg I
Røntgenafdelingen og neurologisk afdeling, Vejle Sygehus.
Ugeskr Laeger. 1995 Jul 3;157(27):3901-4.
Twenty-eight consecutive patients undergoing cervical myelography were examined with either iohexol (14) or iotrolan (14). Just before the myelography a cranial CT was performed and control CT (3-5 slices) examinations were performed three, six, 24 and 48 hours afterwards. In all 28 patients CT showed intracranial contrast medium distribution after cervical myelography. The contrast medium distributed mainly in the subarachnoid space, first to the basal cisterns and the insular fissures, and to the 4th ventricle. The densities in the subarachnoid spaces were significantly higher after iotrolan than iohexol in the basal cisterns three and six hours after myelography, and in the 4th ventricle. The subcortical density was still increasing 48 hours after iotrolanmyelography while the subcortical density reached the maximum 24 hours after iohexolmyelography. Following cervical myelography the contrast media iohexol and iotrolan distribute intracranially and iotrolan seems to be eliminated more slowly than iohexol.
连续28例接受颈椎脊髓造影的患者分别使用碘海醇（14例）或碘曲仑（14例）进行检查。在脊髓造影前即刻进行头颅CT检查，并在之后3小时、6小时、24小时和48小时进行对照CT（3 - 5层）检查。所有28例患者的CT均显示颈椎脊髓造影后颅内造影剂的分布情况。造影剂主要分布在蛛网膜下腔，首先到达脑基底池和脑岛裂，然后到达第四脑室。脊髓造影后3小时和6小时，在脑基底池以及第四脑室内，碘曲仑造影后蛛网膜下腔的密度显著高于碘海醇造影后的密度。碘曲仑脊髓造影后48小时皮质下密度仍在增加，而碘海醇脊髓造影后24小时皮质下密度达到最大值。颈椎脊髓造影后，碘海醇和碘曲仑造影剂在颅内均有分布，且碘曲仑的清除似乎比碘海醇更慢。
