伴有阴茎转移的高恶性前列腺癌的临床和病理特征

Clinical and pathological features of highly malignant prostatic carcinomas with metastases to the penis.

作者信息

Buchholz N P, Moch H, Feichter G E, Schmid H P, Mihatsch M J

机构信息

Clinic of Urology, University Hospital (Kantonsspital) Basel, Switzerland.

出版信息

Urol Int. 1994;53(3):135-8. doi: 10.1159/000282654.

DOI:10.1159/000282654

PMID:7645139

Abstract

Since 1885, 73 penile metastases of a primary carcinoma of the prostate have been reported. There is no standardized therapy as various therapeutic methods have produced variable results. The authors present their experiences with 2 recent cases. In some cases, total penectomy can relieve untolerable pain. Immunohistochemistry and flow cytometry for various prognostic factors showed a high malignant potential of carcinomas of the prostate metastasizing to the penis. Screening for various prognostic factors could favor an initial, more radical surgical approach in some cases, thus avoiding later tumor progression.

摘要

自1885年以来，已有73例前列腺原发性癌阴茎转移的报告。由于各种治疗方法产生的结果各不相同，目前尚无标准化治疗方案。作者介绍了他们最近两例病例的经验。在某些情况下，阴茎全切术可缓解难以忍受的疼痛。针对各种预后因素的免疫组织化学和流式细胞术显示，前列腺癌转移至阴茎具有较高的恶性潜能。对各种预后因素进行筛查可能有助于在某些情况下采取更激进的初始手术方法，从而避免肿瘤后期进展。