Osari S, Muranaka H, Kojima T, Kimura Y
Department of Pediatrics, Hirosaki, University, Japan.
Acta Paediatr Jpn. 1995 Jun;37(3):409-12. doi: 10.1111/j.1442-200x.1995.tb03344.x.
We describe a 6 year old girl with chorea following cardiac surgery, the first such report in Japan. The radical operation for total anomalous pulmonary venous return was carried out at the age of 11 months under hypothermia. Seven days after the operation, a sudden onset of irritability, dysphagia, chorea, generalized, hypotonia, and complete external ophthalmoplegia were seen. These symptoms diminished gradually, but chorea remained. We speculated that the cause of chorea arose from the cardiac surgery under hypothermia. It is necessary to consider 'cardiac surgery' as one of the triggers of certain movement disorders including chorea. We tried treatment with haloperidol, pimozide, and several other drugs; only pimozide was effective in decreasing chorea without any side-effects.
我们描述了一名6岁女童在心脏手术后出现舞蹈症，这是日本首例此类报告。该女童11个月大时在低温状态下接受了完全性肺静脉异位引流根治手术。术后7天，突然出现烦躁、吞咽困难、舞蹈症、全身性肌张力减退及完全性外展神经麻痹。这些症状逐渐减轻，但舞蹈症仍存在。我们推测舞蹈症的病因源于低温下的心脏手术。有必要将“心脏手术”视为包括舞蹈症在内的某些运动障碍的触发因素之一。我们尝试用氟哌啶醇、匹莫齐特及其他几种药物进行治疗；只有匹莫齐特能有效减轻舞蹈症且无任何副作用。
