Pentti J, Salenius J P, Kuukasjärvi P, Tarkka M
Department of Surgery, University Hospital, Tampere, Finland.
Ann Chir Gynaecol. 1995;84(1):25-8.
During a 26 years' period, 547 thromboembolectomies were undertaken for acute limb ischaemia. The portion of upper limb ischaemia was 17.7% (97/547). The annual incidence of surgically treated acute upper limb ischaemia was 1.3 cases/100,000/year during the last 15 years of study period. There were 91 patients, 45 males and 46 females, ranging from 17 to 92 years with a median age of 73 years. Pulselessness (96), coldness (94), pain (85), paraesthesia (45) and dysfunction (45) of the affected limb were the main symptoms. The right upper limb was more often affected (59/38, P < 0.05). An embolus originating from the heart was the reason for the ischaemia in 71 cases, while in 11 cases the occlusion was caused by a local thrombosis. In 15 cases the origin of the embolus remained unsolved. In five cases an additional arterial reconstruction was needed to restore the circulation. Reembolectomy of the same limb was needed in five cases, and additionally in two patients, a third embolectomy was unavoidable. A secondary humeral amputation was necessary for one patient. Eleven patients (11.3%) died within 30 days and of these nine did so from recurrent embolism. The mortality was not related to the duration of the ischaemia, but rather to patients' general condition. During a mean follow-up time of 50 weeks a good functional result was achieved in 78 cases (80.4%). The clinical results in ischaemia caused by embolism are markedly better than those of local thrombosis (P < 0.001).
在26年的时间里,共进行了547例急性肢体缺血血栓切除术。上肢缺血的比例为17.7%(97/547)。在研究期的最后15年中,手术治疗的急性上肢缺血的年发病率为1.3例/10万/年。有91例患者,男性45例,女性46例,年龄在17至92岁之间,中位年龄为73岁。患侧肢体无脉(96例)、发冷(94例)、疼痛(85例)、感觉异常(45例)和功能障碍(45例)是主要症状。右上肢更常受累(59/38,P<0.05)。71例缺血的原因是心脏来源的栓子,而11例闭塞是由局部血栓形成引起的。15例栓子的来源仍未明确。5例需要额外的动脉重建以恢复循环。5例需要对同一肢体进行再次取栓,另外2例患者不可避免地需要进行第三次取栓。1例患者需要进行二期肱骨截肢。11例患者(11.3%)在30天内死亡,其中9例死于复发性栓塞。死亡率与缺血持续时间无关,而与患者的一般状况有关。在平均50周的随访时间里,78例(80.4%)取得了良好的功能结果。栓塞引起的缺血的临床结果明显优于局部血栓形成(P<0.001)。