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[冠状动脉内支架置入术治疗血管成形术并发的威胁生命或闭塞性夹层的即时效果;日内瓦经验]

[Immediate results of coronary endoprosthesis in threatening or occlusive dissections complicating angioplasty; the Geneva experience].

作者信息

Metz D, Urban P, Meier B, Hoang V, Camenzind E, Brzostek T, Chatelain P, Rutishauser W

机构信息

Service de cardiologie, hôpital Robert-Debré, Reims.

出版信息

Arch Mal Coeur Vaiss. 1994 Sep;87(9):1153-9.

PMID:7646228
Abstract

Between April 1988 and September 1993, 123 patients (average age 60.4 +/- 8.9 years) underwent coronary stenting for threatening or occlusive dissection complicating angioplasty. The anterograde coronary flow was disturbed in 51% of cases (TIMI-0-2). The artery concerned was the left anterior descending in 59% of cases, the right coronary in 28% of cases, the circumflex in 12% and a coronary bypass graft in 1% of cases. Technically, the stenting was successful in 118 cases (98%) and, in 21 cases, complete stenting of the dissection required the insertion of several stents. The minimal coronary diameter after expansion of the stent was 3.1 +/- 0.6 mm. During hospital follow-up, 3 deaths (3%) and 7 Q-wave infarcts were observed. Twenty-eight patients (23%) developed a haemorrhagic complication, including 2 retroperitoneal and 2 intracerebral bleeds. Eight patients (6%) underwent coronary bypass grafting, as an emergency in 4 cases and semi-electively in another 4 cases. One hundred and five patients (89%) survived the intra-hospital period without major complications (death, Q-wave infarction, emergency coronary bypass surgery or severe haemorrhage). Coronary stenting for threatening or occlusive dissection complicating angioplasty seems to be a reasonable solution and a usually definitive one. The frequency of haemorrhagic complications underlines the need for strict clinical and biological surveillance.

摘要

1988年4月至1993年9月期间,123例患者(平均年龄60.4±8.9岁)因血管成形术并发的有威胁性或闭塞性夹层而接受冠状动脉支架置入术。51%的病例(TIMI-0-2)出现冠状动脉前向血流紊乱。相关动脉在59%的病例中为左前降支,28%为右冠状动脉,12%为回旋支,1%为冠状动脉旁路移植血管。从技术上讲,118例(98%)支架置入成功,21例病例中,夹层的完全支架置入需要插入多个支架。支架扩张后最小冠状动脉直径为3.1±0.6mm。在住院随访期间,观察到3例死亡(3%)和7例Q波梗死。28例患者(23%)发生出血并发症,包括2例腹膜后出血和2例脑出血。8例患者(6%)接受了冠状动脉旁路移植术,4例为急诊,另4例为半择期手术。105例患者(89%)在住院期间存活且无重大并发症(死亡、Q波梗死、急诊冠状动脉旁路手术或严重出血)。因血管成形术并发的有威胁性或闭塞性夹层进行冠状动脉支架置入术似乎是一种合理的解决方案,通常也是一种确定性的方案。出血并发症的发生率强调了严格临床和生物学监测的必要性。

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