Parrens E, Vergnes M C, Jimenez M, Bouffard P, Dos Santos P, Srour S, Choussat A
Service de cardiologie pédiatrique, hôpital du Haut-Lévêqué, Pessac.
Arch Mal Coeur Vaiss. 1995 May;88(5):771-4.
The authors report the case of a 10 year old child who presented with an uncomplicated deep venous thrombosis associated with an antiphospholipid syndrome. The diagnosis was established by the finding of spontaneous prolongation of the activated cephalin time, the finding of a lupus-like antibody and an anti-cardiolipin antibody. The clinical outcome was good with oral anticoagulants but a recurrence was observed when they were stopped. The authors discuss the question of the duration of preventive therapy.
作者报告了一名10岁儿童的病例,该患儿患有与抗磷脂综合征相关的单纯性深静脉血栓形成。诊断依据是活化部分凝血活酶时间自发延长、发现狼疮样抗体和抗心磷脂抗体。口服抗凝剂治疗的临床效果良好,但停药后出现复发。作者讨论了预防性治疗的持续时间问题。