Capel P
Laboratoire d'Hématologie, Hôpital Erasme, Bruxelles.
Rev Med Brux. 1997 Jun;18(3):108-10.
Antiphospholipid antibodies are associated with venous and arterial thromboembolism and with fetal loss. These associations are found either in autoimmune disease or without any other associated disease. In the first case one will speak of secondary antiphospholipid syndrome and in the second of primary antiphospholipid syndrome. The detection techniques of these antibodies have been improved these last years, although they remain difficult to standardize. The treatment of thromboembolism is based on the use of heparin and oral anticoagulants. Several therapeutic options exist to treat fetal losses, among which corticosteroids, subcutaneous heparin and aspirin are the most frequently used.
抗磷脂抗体与静脉和动脉血栓栓塞以及胎儿丢失有关。这些关联见于自身免疫性疾病或无任何其他相关疾病的情况。在前一种情况下，称为继发性抗磷脂综合征，后一种情况则称为原发性抗磷脂综合征。近年来，这些抗体的检测技术有所改进，尽管它们仍难以标准化。血栓栓塞的治疗基于肝素和口服抗凝剂的使用。有几种治疗胎儿丢失的选择，其中皮质类固醇、皮下注射肝素和阿司匹林是最常用的。
