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[酸枣仁对内毒素发热小鼠超氧化物歧化酶降低的保护作用]

[Protective effect of semen Ziziphi spinosae on superoxide dismutase reduction in mice with endotoxin fever].

作者信息

Peng Z, Zhang H, Cheng S, Guo W

机构信息

Children's Hospital of Wuhan.

出版信息

Zhongguo Zhong Yao Za Zhi. 1995 Jun;20(6):369-70, inside back cover.

PMID:7646811
Abstract

An animal model with decreasing SOD was established by fever from intravenous injection of endotoxin. The SOD level was measured by RIA in the animal serum and liver tissues. The results indicated that the SOD level of the model group was obviously lower than that of the normal group (P < 0.05), but the level of the group treated with Semen Ziziphi Spinosae was higher than that of the model group. The study shows that Semen Ziziphi Spinosae can protect mice with endotoxin fever from SOD decrease.

摘要

通过静脉注射内毒素致热建立超氧化物歧化酶(SOD)降低的动物模型。采用放射免疫分析法(RIA)测定动物血清和肝组织中的SOD水平。结果表明,模型组的SOD水平明显低于正常组(P<0.05),但酸枣仁治疗组的水平高于模型组。研究表明,酸枣仁可保护内毒素发热小鼠的SOD水平降低。

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