Qu N, Wen J K, Li E
TCM-WM Basic Theory Dept., Hebei Medical College, Shijiazhuang.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1995 Apr;15(4):222-4.
The rats were fed with adenine to establish the chronic renal insufficiency anemia model, and the relationship between renal functional impairment and reticulocytes, hemoglobin and erythropoietin (EPO) synthesis was observed to explore the mechanism of Bushen Shengxue drugs in improving the hemopoietic function. The results showed that the Bushen Shengxue drugs could significantly lower the serum creatinine and blood urea nitrogen of renal insufficiency rats, and through the promotion of EPO gene expression, the animals' anemic status was improved.
