[Clinical study on effect of bushen shengxue paste in treating renal anemia patients].

OBJECTIVE

To evaluate the therapeutical mechanism of Bushen Shengxue Paste (BSSXP) on anemia.

METHODS

Chronic renal failure induced anemia patients were treated with BSSXP, clinical manifestation, anemia and renal function as indicators were observed in patients. The erythropoietin (EPO) and inhibition of colony-forming unit-erythrocyte (CFU-E) in patients' serum were determined by CFU-E in vitro.

RESULTS

The patients' symptoms, renal function and anemia were improved after administration with BSSXP 1-2 course. EPO in serum was slightly increased. The inhibition of CFU-E in patient's serum was significantly decreased.

CONCLUSIONS

BSSXP could improve the anemia degree, its mechanism might be through clearing the inhibitor of CFU-E in serum.