念珠菌病中类似TH1-TH2的转变：治疗新视角
A TH1-TH2-like switch in candidiasis: new perspectives for therapy.
作者信息
Puccetti P, Romani L, Bistoni F
机构信息
Dept of Experimental Medicine, University of Rome Tor Vergata, Italy.
出版信息
Trends Microbiol. 1995 Jun;3(6):237-40. doi: 10.1016/s0966-842x(00)88931-3.
PMID:7648032
Abstract
An imbalance in TH1-type and TH2-type responses may allow Candida albicans to modify the host response to favor its own persistence. This hypothesis has important consequences for allergy, autoimmunity and co-infection, and also highlights a potential role for cytokine and anti-cytokine therapy in Candida-related pathology.
摘要
TH1型和TH2型反应的失衡可能会使白色念珠菌改变宿主反应，以利于自身持续存在。这一假说对过敏、自身免疫和合并感染具有重要意义，也凸显了细胞因子和抗细胞因子疗法在念珠菌相关病理中的潜在作用。
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