Ruppel K M, Lorenz M, Spudich J A
Department of Biochemistry and Developmental Biology, Stanford University School of Medicine, CA 94305, USA.
Curr Opin Struct Biol. 1995 Apr;5(2):181-6. doi: 10.1016/0959-440x(95)80073-5.
In the past year, the structure of the regulatory domain of scallop myosin has joined that of the chicken skeletal muscle myosin subfragment 1 and provided insights into the regulation of myosin function. Mutagenesis studies in a variety of systems have used the information provided by these structures to create mutant myosins to test models of chemomechanical transduction and its regulation.
