Holt R D
Department of Children's Dentistry, Eastman Dental Institute for Oral and Dental Health Care Sciences, London, UK.
Community Dent Health. 1995 Jun;12(2):93-9.
A group of 1,006 children examined at 5 years of age was followed up after a further four year period. Thirty seven per cent of the group had some caries experience at the age of 5 years. Four years later this proportion had increased to 52 per cent. There was little caries in incisor teeth at the age of 5 with the disease affecting mainly primary molars, (especially second primary molars) and occlusal surfaces. Primary molars continued to experience new attack in the subsequent four years, with lesions affecting more first primary molars and more approximal than occlusal surfaces during this period. New caries was seen most often in children with previous disease experience but children with a lower dmfs of between 1 and 5 at 5 years experienced a similar increment to those with more extensive caries (dmfs > or = 6). In contrast, few lesions were seen in the children who had been caries free at 5 years. Children in the study had taken part in a trial of a lower fluoride toothpaste (550ppmF) especially formulated for young children. There was no difference in relative pattern of disease in test and control groups but the trend seen at the end of the trial for children who had used the test paste to have slightly higher levels of disease than those who had used a standard control paste (1,055ppmF) was seen again four years later.
一组1006名5岁儿童在经过四年的随访期后再次接受检查。该组中有37%的儿童在5岁时已有龋齿经历。四年后，这一比例升至52%。5岁时切牙很少发生龋齿，患病主要累及乳磨牙（尤其是第二乳磨牙）及咬合面。在随后的四年中，乳磨牙继续出现新的龋损，在此期间，第一乳磨牙和邻面龋损比咬合面更多。新龋最常出现在曾有过龋齿经历的儿童中，但5岁时dmfs在1至5之间的儿童的龋损增加情况与龋损范围更广（dmfs≥6）的儿童相似。相比之下，5岁时无龋的儿童几乎没有出现龋损。该研究中的儿童参与了一项专为幼儿配制的低氟牙膏（含氟量550ppm）试验。试验组和对照组的疾病相对模式没有差异，但在试验结束时，使用试验牙膏的儿童的疾病水平略高于使用标准对照牙膏（含氟量1055ppm）的儿童，四年后再次出现了这种趋势。
