Karacagil S, Almgren B, Bowald S, Bergqvist D
Department of Surgery, University Hospital, Uppsala, Sweden.
Diabet Med. 1995 Jun;12(6):537-41. doi: 10.1111/j.1464-5491.1995.tb00537.x.
In 92 diabetic and 175 non-diabetic patients undergoing 336 femoropopliteal or femorodistal bypass procedures, 1- and 3-year cumulative life-table patency, limb salvage, and survival rates were comparatively analysed. The peroperative mortality rate was significantly higher in diabetic patients (5% compared to 1.4%, p < 0.001). The cumulative graft patency rates were 61% at 12 months and 46% at 36 months in diabetic patients compared to 64 and 52% in non-diabetic patients. Significantly better patency rates were observed in limbs with good runoff compared to limbs with poor runoff in both groups. The limb salvage rates at 3 years were 70% in diabetic patients and 62% in non-diabetic patients. The survival rate at 3 years was significantly lower in diabetic patients, 62% compared to 86% in non-diabetic patients. Diabetic patients with poor runoff demonstrated a significantly lower survival rate after 36 months compared to diabetic patients with good runoff (48% and 74%, respectively). The results of this study demonstrate that the early and intermediate patency and limb salvage rates are similar in diabetic and non-diabetic patients. On the other hand the survival rate in diabetic patients, especially in those with poor distal runoff, is significantly lower than non-diabetic patients.
在92例糖尿病患者和175例非糖尿病患者接受336次股腘或股胫动脉搭桥手术中，对1年和3年的累积生命表通畅率、肢体挽救率和生存率进行了比较分析。糖尿病患者的围手术期死亡率显著更高（5% 对比1.4%，p < 0.001）。糖尿病患者12个月时的累积移植物通畅率为61%，36个月时为46%，而非糖尿病患者分别为64%和52%。两组中，与血流不佳的肢体相比，血流良好的肢体观察到显著更高的通畅率。糖尿病患者3年时的肢体挽救率为70%，非糖尿病患者为62%。糖尿病患者3年时的生存率显著更低，为62%，而非糖尿病患者为86%。与血流良好的糖尿病患者相比，血流不佳的糖尿病患者36个月后的生存率显著更低（分别为48%和74%）。本研究结果表明，糖尿病患者和非糖尿病患者的早期和中期通畅率及肢体挽救率相似。另一方面，糖尿病患者的生存率，尤其是远端血流不佳的患者，显著低于非糖尿病患者。
