Tang P, Gao M, Cao D
Beijing Red Cross Chaoyang Hospital.
Zhonghua Nei Ke Za Zhi. 1995 Mar;34(3):185-9.
The necropsy findings of 18 patients with cor pulmonale and coronary heart disease (CHD) were compared with those of a control group of 30 patients with cor pulmonale alone. The results showed that there was no significant statistical difference between the two groups on average heart weight and average left and right ventricular thickness (P > 0.05). The results suggest that at the end stage of cor pulmonale left ventricule may be involved whether there are complicating left ventricular disease or not. In this study, cor pulmonale and CHD were both accurately diagnosed in 33.3%, CHD failed to be diagnosed in 38.9% and cor pulmonale failed to be diagnosed in 27.8% of the patients. Single diagnostic factor analysis for cor pulmonale with CHD indicated that age, history of hypertension, history of angina pectoris, history of MI, accentuation A2, presence of bundle branch block, abnormal Q wave and left axis or normal deviation, Cheng Xiansheng diagostic criteria and Selvester MI screening criteria are of significance (P < 0.05). Multiple factor logistic regression analysis indicated that independent prognostic factors including history of angina pectoris, Selvester MI screening criteria and Cheng Xiansheng diagnostic criteria are of help for diagnosis (P < 0.03-0.000). The above-mentioned diagnostic methods are, however, not so specific. At present the best method for diagnosis of CHD is coronary arteriography.
对18例肺心病合并冠心病患者的尸检结果与30例单纯肺心病对照组患者的尸检结果进行了比较。结果显示,两组在平均心脏重量以及平均左、右心室厚度方面无显著统计学差异(P>0.05)。结果表明,在肺心病终末期,无论是否合并左心室疾病,左心室均可能受累。本研究中,33.3%的患者肺心病和冠心病均被准确诊断,38.9%的患者冠心病未被诊断,27.8%的患者肺心病未被诊断。对肺心病合并冠心病的单一诊断因素分析表明,年龄、高血压病史、心绞痛病史、心肌梗死病史、A2亢进、束支传导阻滞、异常Q波、电轴左偏或正常、陈先生诊断标准以及塞尔维斯特心肌梗死筛查标准具有显著性意义(P<0.05)。多因素逻辑回归分析表明,包括心绞痛病史、塞尔维斯特心肌梗死筛查标准和陈先生诊断标准在内的独立预后因素有助于诊断(P<0.03-0.000)。然而,上述诊断方法并非特异性很强。目前诊断冠心病的最佳方法是冠状动脉造影。