Lewczuk J, Piszko P, Jagas J, Porada A, Spikowski J, Wrabec K
Oddziału Internistyczno-Kardiologicznego Wojewódzkiego Szpitala Specjalistycznego, Wrocławiu.
Pol Merkur Lekarski. 1997 Aug;3(14):68-70.
Electrocardiogram is commonly used in the diagnosis of cor pulmonale in patients with chronic obstructive pulmonary disease (COPD). Pulmonary hemodynamics being the definite method for diagnosis the disease can be used to vary the ecg criteria for diagnosis cor pulmonale. After excluding patients with old myocardial infarction and with pulmonary wedge pressure > 12 mm Hg in 66 patients aged 65.2 with advanced COPD (FEV1 0.78 +/- 0.3 litre) pulmonary hemodynamics and ecg were performed at the same time. The signs of right ventricular hypertrophy were sought for using 3 sets of criteria: the World Health Organisation criteria, new compiled Lehtonen et al. Criteria and right ventricular precordial leads. WHO criteria had a specificity and sensitivity of 50% and 57.6%, the modified right precordial leads-53% and 64.5% and compiled Lehtonen's criteria -57% and 59% respectively. In 32 patients with mild pulmonary hypertension (20-29 mm Hg) sensitivity of WHO criteria was 46.8%, right precordial leads -51.6%, and Lethonen and co. Criteria -50%, in 10 patients with moderate pulmonary hypertension (30-39 mm Hg) 59%-62.5%-50%, in 9 patients with severe hypertension (> or = 40 mm Hg) 100%-100%-100% respectively. Our studies confirm the poor sensitivity and of ecg criteria for diagnosis of cor pulmonale (pulmonary hypertension) in COPD. However, in mild and moderate pulmonary hypertension, sensitivity of ecg diagnosis of cor pulmonale is improved if right modifieds precordial leads are used. New, compiled Lehtonen's criteria failed to improved diagnosis of diagnosis of cor pulmonale. All studied sets of criteria are highly sensitive in COPD patients with severe pulmonary hypertension.
心电图常用于慢性阻塞性肺疾病(COPD)患者肺心病的诊断。肺血流动力学作为诊断该病的金标准,可用于改变肺心病的心电图诊断标准。在66例年龄为65.2岁、患有晚期COPD(FEV1为0.78±0.3升)的患者中,排除陈旧性心肌梗死患者及肺楔压>12 mmHg的患者后,同时进行肺血流动力学和心电图检查。采用3套标准寻找右心室肥厚的征象:世界卫生组织标准、新编制的Lehtonen等人的标准以及右心室胸前导联。世界卫生组织标准的特异性和敏感性分别为50%和57.6%,改良的右胸前导联为53%和64.5%,编制的Lehtonen标准为57%和59%。在32例轻度肺动脉高压(20 - 29 mmHg)患者中,世界卫生组织标准的敏感性为46.8%,右胸前导联为51.6%,Lethonen等人的标准为50%;在10例中度肺动脉高压(30 - 39 mmHg)患者中,分别为59% - 62.5% - 50%;在9例重度高血压(≥40 mmHg)患者中,分别为100% - 100% - 100%。我们的研究证实,COPD患者肺心病(肺动脉高压)诊断的心电图标准敏感性较差。然而,在轻度和中度肺动脉高压中,使用改良的右胸前导联可提高肺心病心电图诊断的敏感性。新编制的Lehtonen标准未能改善肺心病的诊断。所有研究的标准集在重度肺动脉高压的COPD患者中敏感性都很高。