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[同种异体移植人肾球旁器的形态计量学]

[Morphometry of the juxtaglomerular apparatus of allo-transplanted human kidneys].

作者信息

Orduian S L, Bliumkin V N

出版信息

Biull Eksp Biol Med. 1976 Jan;81(1):87-8.

PMID:764900
Abstract

Juxtaglomerular appartus of 17 allotransplanted human kidneys was studied by the karyometric method at various periods of existence in the recipient's organism. Kidneys of persons who died of craniocerebral trauma or acute cardiac incompetence served as control. At the early periods (up to 2 months) there was revealed an authentic increase in the nuclear volume of the epitheloid-modified cells of the afferent arteriole and of the Goormaghtigh cells. There was also a tendency to increase in the volume of the macula densa cells. At the late periods the juxtamolecular apparatus persisted in the allotransplanted kidneys with a but little injured parenchyma. Reduction of the juxtaglomerular appartus occurred in case of marked sclerosis and atrophy of the transplant parenchyma.

摘要

应用核测量法对17例同种异体移植人肾的球旁器在受者机体内存活的不同时期进行了研究。以死于颅脑外伤或急性心功能不全者的肾脏作为对照。在早期(至2个月),发现入球小动脉上皮样细胞和球旁细胞的核体积确实增大。致密斑细胞体积也有增大趋势。晚期,在实质损伤轻微的同种异体移植肾中球旁器依然存在。移植肾实质显著硬化和萎缩时,球旁器则缩小。

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