Van der Vusse G J, Roemen T H
Department of Physiology, University of Limburg, Maastricht, The Netherlands.
J Appl Physiol (1985). 1995 May;78(5):1839-43. doi: 10.1152/jappl.1995.78.5.1839.
In anesthetized dogs, the amount of fatty acyl moieties in the fatty acid, triacylglycerol, and phospholipid fractions of arterial blood and biceps femoris muscle has been determined to delineate the presence of a fatty acid gradient from blood to skeletal muscle tissue, if any. The content of fatty acids in biceps femoris muscle was found to be very low (approximately 0.1% of total amount of unesterified and esterified fatty acyl moieties in the tissue sample). The ratio of the content of fatty acids (nmol/ml) in arterial plasma and the tissue level of fatty acids (nmol/g wet weight) was approximately 17. This finding supports the notion that a fatty acid gradient from the vascular compartment to the skeletal muscle fibers might be one of the driving forces of net extraction of fatty acids by skeletal muscle.
在麻醉犬中，已测定动脉血和股二头肌中脂肪酸、三酰甘油和磷脂部分的脂肪酰基部分的含量，以确定从血液到骨骼肌组织是否存在脂肪酸梯度（如果存在的话）。发现股二头肌中的脂肪酸含量非常低（约占组织样本中未酯化和酯化脂肪酰基部分总量的0.1%）。动脉血浆中脂肪酸含量（nmol/ml）与组织中脂肪酸水平（nmol/g湿重）的比值约为17。这一发现支持了这样一种观点，即从血管腔到骨骼肌纤维的脂肪酸梯度可能是骨骼肌净摄取脂肪酸的驱动力之一。
