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抗精神病药物与迟发性运动障碍:青少年精神科病房的初步结果

Antipsychotic drugs and tardive dyskinesia: preliminary results in an adolescent psychiatric ward.

作者信息

Dorevitch A, Meretyk I, Umansky Y, Galili-Weisstub E

机构信息

Talbieh Mental Health Center, Jerusalem, Israel.

出版信息

J Clin Pharm Ther. 1995 Apr;20(2):63-5. doi: 10.1111/j.1365-2710.1995.tb00630.x.

Abstract

The systematic study of antipsychotic-induced movement disorders in young psychiatric patients is very sparse. We assessed the presence of tardive dyskinesia in an adolescent in-patient psychiatric ward. Eighteen per cent (3/17) exhibited either pronounced or subtle signs of tardive dyskinesia. Our study suggests that young psychiatric patients may develop signs of tardive dyskinesia even though they are exposed to relatively short-term neuroleptic treatment and at dosages that are relatively low. We advocate frequent and systematic monitoring of adolescent patients taking antipsychotic drugs in order to minimize the emergence of this long-term, troublesome complication of neuroleptic drugs.

摘要

针对年轻精神科患者抗精神病药物所致运动障碍的系统性研究非常匮乏。我们评估了一所青少年住院精神科病房中迟发性运动障碍的发生情况。18%(3/17)的患者表现出明显或轻微的迟发性运动障碍体征。我们的研究表明,尽管年轻精神科患者接受的是相对短期的抗精神病药物治疗,且剂量相对较低,但仍可能出现迟发性运动障碍体征。我们主张对服用抗精神病药物的青少年患者进行频繁且系统的监测,以尽量减少这种抗精神病药物长期所致的麻烦并发症的出现。

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